Article
Phenotyping the Preterm Brain: Characterizing Individual Deviations From Normative Volumetric Development in Two Large Infant Cohorts.
Cerebral cortex (New York, N.Y. : 1991) - 5 Jul 2021
Dimitrova Ralica, Arulkumaran Sophie, Carney Olivia, Chew Andrew, Falconer Shona, Ciarrusta Judit, Wolfers Thomas, Batalle Dafnis, Cordero-Grande Lucilio, Price Anthony N, Teixeira Rui P A G, Hughes Emer, Egloff Alexia, Hutter Jana, Makropoulos Antonios, Robinson Emma C, Schuh Andreas, Vecchiato Katy, Steinweg Johannes K, Macleod Russell, Marquand Andre F, McAlonan Grainne, Rutherford Mary A, Counsell Serena J, Smith Stephen M, Rueckert Daniel, Hajnal Joseph V, O'Muircheartaigh Jonathan, Edwards A David
Abstract excerpt
The diverse cerebral consequences of preterm birth create significant challenges for understanding pathogenesis or predicting later outcome. Instead of focusing on describing effects common to the group, comparing individual infants against robust normative data offers a powerful alternative to study brain maturation. Here we used Gaussian process regression to create normative curves characterizing brain...
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