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Terminal Schwann Cell Aging: Implications for Age-Associated Neuromuscular Dysfunction

1 Jan 2021

Abstract excerpt

Action potential is transmitted to muscle fibers through specialized synaptic interfaces called neuromuscular junctions (NMJs). These structures are capped by terminal Schwann cells (tSCs), which play essential roles during formation and maintenance of the NMJ. tSCs are implicated in the correct communication between nerves and muscles, and in reinnervation upon injury. During aging, loss of muscle mass and...

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PMID: 33815879
DOI: 10.14336/ad.2020.0708

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