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Article

iVar, an Interpretation-Oriented Tool to Manage the Update and Revision of Variant Annotation and Classification.

Genes - 8 Mar 2021

Castellano Sara, Cestari Federica, Faglioni Giovanni, Tenedini Elena, Marino Marco, Artuso Lucia, Manfredini Rossella, Luppi Mario, Trenti Tommaso, Tagliafico Enrico

Abstract excerpt

The rapid evolution of Next Generation Sequencing in clinical settings, and the resulting challenge of variant reinterpretation given the constantly updated information, require robust data management systems and organized approaches. In this paper, we present iVar: a freely available and highly customizable tool with a user-friendly web interface. It represents a platform for the unified management of variants...

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Identifiers

PMID: 33800487
DOI: 10.3390/genes12030384
PMCID: PMC8001268

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