Article
Short Communication: Integrase Strand Transfer Inhibitors Drug Resistance Mutations in Puerto Rico HIV-Positive Individuals.
International journal of environmental research and public health - 8 Mar 2021
López Pablo, Tirado Grissell, Arias Andrea, Sánchez Raphael, Rodríguez-López Elliott R, Rivera-Amill Vanessa
Abstract excerpt
The HIV-1 integrase viral protein is responsible for incorporating the viral DNA into the genomic DNA. The inhibition of viral integration into host cell DNA is part of recent therapeutic procedures. Combination therapy with protease and reverse transcriptase inhibitors has demonstrated good synergistic results in reducing viral replication. The purpose of this study is to assess the occurrence of integrase drug...
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