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Molecular diversity of Mycobacterium tuberculosis complex in Sikkim, India and prediction of dominant spoligotypes using artificial intelligence.

Scientific reports - 1 Apr 2021

Devi Kangjam Rekha, Pradhan Jagat, Bhutia Rinchenla, Dadul Peggy, Sarkar Atanu, Gohain Nitumoni, Narain Kanwar

Abstract excerpt

In India, tuberculosis is an enormous public health problem. This study provides the first description of molecular diversity of the Mycobacterium tuberculosis complex (MTBC) from Sikkim, India. A total of 399 Acid Fast Bacilli sputum positive samples were cultured on Lőwenstein-Jensen media and genetic characterisation was done by spoligotyping and 24-loci MIRU-VNTR typing. Spoligotyping revealed the occurrence...

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PMID: 33795751
DOI: 10.1038/s41598-021-86626-z
PMCID: PMC8016865

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