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Article

All for one and one for all: heterogeneity of genetic etiologies in neurodevelopmental psychiatric disorders.

Current opinion in genetics & development - 1 Jun 2021

Moreno-De-Luca Daniel, Martin Christa Lese

Abstract excerpt

Alexandre Dumas' famous phrase All for One and One for All recapitulates our current understanding of the genomic architecture of neurodevelopmental psychiatric disorders (NPD), like autism Spectrum disorder, bipolar disorder, and schizophrenia. Many rare genomic variants of large effect size have been identified; all of them together can explain a significant proportion of NPD. In parallel, one rare genomic...

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Identifiers

PMID: 33773394
DOI: 10.1016/j.gde.2021.02.015
PMCID: PMC8205958

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