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Article

Identification and validation of a five-gene prognostic signature for hepatocellular carcinoma

26 Mar 2021

Abstract excerpt

BACKGROUND: ARID1A is a commonly mutated tumor suppressor gene found in all human cancer types, but its clinical significance, oncogenic functions, and relevant mechanisms in hepatocellular carcinoma (HCC) are not well understood. OBJECTIVE: We aimed to improving the prognosis risk classification of HCC from the perspective of ARID1A mutations. MATERIALS AND METHODS: We examined the interaction between ARID1A...

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PMID: 33771191
DOI: 10.1186/s12957-021-02202-9

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