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Article

Aging Phenotypes and Restoring Functional Deficits in Older Adults With Hematologic Malignancy.

Journal of the National Comprehensive Cancer Network : JNCCN - 26 Mar 2021

Rosko Ashley E, Wall Sarah, Baiocchi Robert, Benson Don M, Brammer Jonathan E, Byrd John C, Efebera Yvonne A, Maddocks Kami, Rogers Kerry A, Jones Desiree, Sucheston-Campbell Lara, Tang Hancong, Ozer Hatice Gulcin, Huang Ying, Burd Christin E, Naughton Michelle J

Abstract excerpt

BACKGROUND: Gauging fitness remains a challenge among older adults with hematologic malignancies, and interventions to restore function are lacking. We pilot a structured exercise intervention and novel biologic correlates of aging using epigenetic clocks and markers of immunosenescence to evaluate changes in function and clinical outcomes. METHODS: Older adults (n=30) with hematologic malignancy actively...

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Identifiers

PMID: 33770752
DOI: 10.6004/jnccn.2020.7686
PMCID: PMC8600896

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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