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Article

Drivers of linkage disequilibrium across a species' geographic range.

PLoS genetics - 1 Mar 2021

Lucek Kay, Willi Yvonne

Abstract excerpt

While linkage disequilibrium (LD) is an important parameter in genetics and evolutionary biology, the drivers of LD remain elusive. Using whole-genome sequences from across a species' range, we assessed the impact of demographic history and mating system on LD. Both range expansion and a shift from outcrossing to selfing in North American Arabidopsis lyrata were associated with increased average genome-wide LD....

Topics

Alleles
Arabidopsis
Biological Evolution
Drosophila Proteins
Genetic Variation
Genome, Plant
Genomics
Linkage Disequilibrium
Phylogeography
Polymorphism, Single Nucleotide
Recombination, Genetic

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PMID: 33770075
DOI: 10.1371/journal.pgen.1009477
PMCID: PMC8026057

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