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Article

Influence of genetics and the pre-vaccination blood transcriptome on the variability of antibody levels after vaccination against Mycoplasma hyopneumoniae in pigs.

Genetics, selection, evolution : GSE - 18 Mar 2021

Blanc Fany, Maroilley Tatiana, Revilla Manuel, Lemonnier Gaëtan, Leplat Jean-Jacques, Billon Yvon, Ravon Laure, Bouchez Olivier, Bidanel Jean-Pierre, Bed'Hom Bertrand, Pinard-van der Laan Marie-Hélène, Estellé Jordi, Rogel-Gaillard Claire

Abstract excerpt

BACKGROUND: The impact of individual genetic and genomic variations on immune responses is an emerging lever investigated in vaccination strategies. In our study, we used genetic and pre-vaccination blood transcriptomic data to study vaccine effectiveness in pigs. RESULTS: A cohort of 182 Large White pigs was vaccinated against Mycoplasma hyopneumoniae (M. hyo) at weaning (28 days of age), with a booster 21 days...

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Identifiers

PMID: 33731010
DOI: 10.1186/s12711-021-00614-5
PMCID: PMC7972226

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