Article
Staphylococcus aureus genotype variation among and within periprosthetic joint infections.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Feb 2022
Ma Dongzhu, Brothers Kimberly M, Maher Patrick L, Phillips Nathan J, Simonetti Deborah, William Pasculle Anthony, Richardson Anthony R, Cooper Vaughn S, Urish Kenneth L
Abstract excerpt
Staphylococcus aureus is a common organism in orthopedic infections, but little is known about the genetic diversity of strains during an infectious process. Using periprosthetic joint infection (PJI) as a model, a prospective study was designed to quantify genetic variation among S. aureus strains both among and within patients. Whole genome sequencing and multilocus sequence typing was performed to genotype...
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