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Differential expression analysis and profiling of hepatic miRNA and isomiRNA in dengue hemorrhagic fever

10 Mar 2021

Abstract excerpt

Dengue virus causes dengue hemorrhagic fever (DHF) and has been associated to fatal cases worldwide. The liver is one of the most important target tissues in severe cases, due to its intense viral replication and metabolic role. microRNAs role during infection is crucial to understand the regulatory mechanisms of DENV infection and can help in diagnostic and anti-viral therapies development. We sequenced the...

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PMID: 33692368
DOI: 10.1038/s41598-020-72892-w

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