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Profiles of immune cell infiltration and immune-related genes in the tumor microenvironment of esophageal squamous cell carcinoma

10 Mar 2021

Abstract excerpt

BACKGROUND: As a complex system participating in tumor development and progression, the tumor microenvironment was poorly understood in esophageal cancer especially squamous cell carcinoma (ESCC). METHODS: ESTIMATE algorithm is used to investigate tumor-infiltrating immune cells and prognostic genes which were associated with the tumor microenvironment in ESCC. RESULTS: Based on the immune and stromal scores,...

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PMID: 33691689
DOI: 10.1186/s12920-021-00928-9

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