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Identification and validation of three core genes in p53 signaling pathway in hepatitis B virus-related hepatocellular carcinoma

8 Mar 2021

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma (HCC) is a common cancer and the leading cause is persistent hepatitis B virus (HBV) infection. We aimed to identify some core genes and pathways for HBV-related HCC. METHODS: Gene expression profiles of GSE62232, GSE121248, and GSE94660 were available from Gene Expression Omnibus (GEO). The GSE62232 and GSE121248 profiles were the analysis datasets and GSE94660 was the...

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PMID: 33685467
DOI: 10.1186/s12957-021-02174-w

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