Article
Worldwide variation of the COL14A1 gene is shaped by genetic drift rather than selective pressure.
Molecular genetics & genomic medicine - 1 Apr 2021
Calò Carla M, Onali Federico, Robledo Renato, Flore Laura, Massidda Myosotis, Francalacci Paolo
Abstract excerpt
BACKGROUND: The aim of this study is to analyze the worldwide distribution of SNP rs4870723 in COL14A1 gene to check if there are significant genetic differences among different populations and to test if the gene is a trait under selection. METHODS: Genomic DNA was extracted from 69 unrelated individuals from Sardinia and genotyped for SNP rs4870723. Data were compared with 26 different populations, clustered in...
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