Article
Genomic epidemiology of COVID-19 in care homes in the east of England.
eLife - 2 Mar 2021
Hamilton William L, Tonkin-Hill Gerry, Smith Emily R, Aggarwal Dinesh, Houldcroft Charlotte J, Warne Ben, Meredith Luke W, Hosmillo Myra, Jahun Aminu S, Curran Martin D, Parmar Surendra, Caller Laura G, Caddy Sarah L, Khokhar Fahad A, Yakovleva Anna, Hall Grant, Feltwell Theresa, Pinckert Malte L, Georgana Iliana, Chaudhry Yasmin, Brown Colin S, Gonçalves Sonia, Amato Roberto, Harrison Ewan M, Brown Nicholas M, Beale Mathew A, Spencer Chapman Michael, Jackson David K, Johnston Ian, Alderton Alex, Sillitoe John, Langford Cordelia, Dougan Gordon, Peacock Sharon J, Kwiatowski Dominic P, Goodfellow Ian G, Torok M Estee
Abstract excerpt
COVID-19 poses a major challenge to care homes, as SARS-CoV-2 is readily transmitted and causes disproportionately severe disease in older people. Here, 1167 residents from 337 care homes were identified from a dataset of 6600 COVID-19 cases from the East of England. Older age and being a care home resident were associated with increased mortality. SARS-CoV-2 genomes were available for 700 residents from 292 care...
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