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Article

Applicability of ancestral genotyping in pharmacogenomic research with hormonal contraception.

Clinical and translational science - 1 Sept 2021

Lazorwitz Aaron, Aquilante Christina L, Shortt Jonathan A, Sheeder Jeanelle, Teal Stephanie, Gignoux Christopher R

Abstract excerpt

To compare etonogestrel pharmacokinetic and pharmacodynamic outcomes by both self-reported race/ethnicity and genetically determined ancestry among contraceptive implant users. We conducted a secondary analysis of our parent pharmacogenomic study of 350 implant users. We genotyped these reproductive-aged (18-45 years) women for 88 ancestry-informative single nucleotide polymorphisms. We then assigned each...

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Identifiers

PMID: 33650294
DOI: 10.1111/cts.13014
PMCID: PMC8504805

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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