Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rapid, Ultrasensitive, and Highly Specific Diagnosis of COVID-19 by CRISPR-Based Detection

1 Mar 2021

Abstract excerpt

etection to develop a novel diagnostic test (MCCD) and applied for the diagnosis of COVID-19, called COVID-19 MCCD. The MCCD protocol conducts reverse transcription MCDA (RT-MCDA) reaction for RNA templates followed by CRISPR-Cas12a/CrRNA complex detection of predefined target sequences after which degradation of a single-strand DNA (ssDNA) molecule confirms detection of the target sequence. Two MCDA primer sets...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced biosensing and bioanalysis techniques
Share to CRISPR and Genetic Engineering
Share to SARS-CoV-2 detection and testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33645226
DOI: 10.1021/acssensors.0c01984

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rapid, Ultrasensitive, and Highly Specific Diagnosis of COVID-19 by CRISPR-Based DetectionPMID 33645226Read ↗

CRISPR-based biosensing systems: a way to rapidly diagnose COVID-19Semantic proximity Read ↗

Advancing CRISPR-Based Solutions for COVID-19 Diagnosis and TherapeuticsSemantic proximity Read ↗

CRISPR Systems for COVID-19 DiagnosisSemantic proximity Read ↗

Recent progress on rapid SARS-CoV-2/COVID-19 detection by CRISPR-Cas13-based platformsSemantic proximity Read ↗

Advancements in detection of SARS-CoV-2 infection for confronting COVID-19 pandemics.Semantic proximity Read ↗

Development and evaluation of a rapid CRISPR-based diagnostic for COVID-19Semantic proximity Read ↗

CRISPR-Cas12a-Based Detection for the Major SARS-CoV-2 Variants of Concern.Semantic proximity Read ↗

Highly Sensitive Detection Method for HV69-70del in SARS-CoV-2 Alpha and Omicron Variants Based on CRISPR/Cas13aSemantic proximity Read ↗

Potential of CRISPR/Cas system in the diagnosis of COVID-19 infectionSemantic proximity Read ↗

Detection of Infectious Viruses Using CRISPR-Cas12-Based AssaySemantic proximity Read ↗

Molecular diagnostic assays for COVID-19: an overviewSemantic proximity Read ↗

CRISPR-Based COVID-19 Testing: Toward Next-Generation Point-of-Care DiagnosticsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.