Recursive ensemble feature selection provides a robust mRNA expression signature for myalgic encephalomyelitis/chronic fatigue syndrome

Abstract excerpt

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic disorder characterized by disabling fatigue. Several studies have sought to identify diagnostic biomarkers, with varying results. Here, we innovate this process by combining both mRNA expression and DNA methylation data. We performed recursive ensemble feature selection (REFS) on publicly available mRNA expression data in peripheral blood...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Fibromyalgia and Chronic Fatigue Syndrome Research
• Share to IL-33, ST2, and ILC Pathways
• Share to Osteoarthritis Treatment and Mechanisms