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Mutations introduced in susceptibility genes through CRISPR/Cas9 genome editing confer increased late blight resistance in potatoes.

Scientific reports - 24 Feb 2021

Kieu Nam Phuong, Lenman Marit, Wang Eu Sheng, Petersen Bent Larsen, Andreasson Erik

Abstract excerpt

The use of pathogen-resistant cultivars is expected to increase yield and decrease fungicide use in agriculture. However, in potato breeding, increased resistance obtained via resistance genes (R-genes) is hampered because R-gene(s) are often specific for a pathogen race and can be quickly overcome by the evolution of the pathogen. In parallel, susceptibility genes (S-genes) are important for pathogenesis, and...

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PMID: 33627728
DOI: 10.1038/s41598-021-83972-w
PMCID: PMC7904907

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