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Integrins mediate placental extracellular vesicle trafficking to lung and liver in vivo

18 Feb 2021

Abstract excerpt

Membrane-bound extracellular vesicles (EVs) mediate intercellular communication in all organisms, and those produced by placental mammals have become increasingly recognized as significant mediators of fetal-maternal communication. Here, we aimed to identify maternal cells targeted by placental EVs and elucidate the mechanisms by which they traffic to these cells. Exogenously administered pregnancy-associated EVs...

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PMID: 33602965
DOI: 10.1038/s41598-021-82752-w

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