Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantifying Live Microbial Load in Human Saliva Samples over Time Reveals Stable Composition and Dynamic Load

15 Feb 2021

Abstract excerpt

Human microbiomes are dynamic ecosystems often composed of hundreds of unique microbial taxa. To detect fluctuations over time in the human oral microbiome, we developed a novel workflow to quantify live microbial cells with flow cytometry in parallel with next-generation sequencing, and applied this method to over 150 unstimulated, timed saliva samples. Microbial load was inversely correlated with salivary flow...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gut microbiota and health
Share to Oral microbiology and periodontitis research
Share to Salivary Gland Disorders and Functions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33594005
DOI: 10.1128/msystems.01182-20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantifying Live Microbial Load in Human Saliva Samples over Time Reveals Stable Composition and Dynamic LoadPMID 33594005Read ↗

The salivary microbiome shows a high prevalence of core bacterial members yet variability across human populationsSemantic proximity Read ↗

The human salivary microbiome exhibits temporal stability in bacterial diversitySemantic proximity Read ↗

Study of inter- and intra-individual variations in the salivary microbiota.Semantic proximity Read ↗

Inter-Individual Differences in the Oral Bacteriome Are Greater than Intra-Day Fluctuations in IndividualsSemantic proximity Read ↗

A clinically validated human saliva metatranscriptomic test for global systems biology studiesSemantic proximity Read ↗

Factors influencing oral microbiome analysis: from saliva sampling methods to next-generation sequencing platformsSemantic proximity Read ↗

Sequencing depth overcomes extraction bias: repurposing human WGS data for salivary microbiome profilingSemantic proximity Read ↗

Absolute quantification of the living skin microbiome overcomes relic-DNA bias and reveals specific patterns across volunteersSemantic proximity Read ↗

The saliva microbiome profiles are minimally affected by collection method or DNA extraction protocolsSemantic proximity Read ↗

Microbial Community Profiling of Human Saliva Using Shotgun Metagenomic SequencingSemantic proximity Read ↗

Tracing the accumulation of in vivo human oral microbiota elucidates microbial community dynamics at the gateway to the GI tractSemantic proximity Read ↗

Longitudinal Saliva Omics Responses to Immune Perturbation: A Case StudySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.