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Perturbations of morphogenesis at the compaction stage affect blastocyst implantation and live birth rates

19 Jan 2021

Abstract excerpt

STUDY QUESTION: Do perturbations of embryo morphogenesis at compaction affect blastocyst development and clinical outcomes in assisted reproduction cycles? SUMMARY ANSWER: Cell exclusion and extrusion, i.e. cell disposal occurring respectively before or during morula compaction, affect blastocyst yield and quality, as well as rates of pregnancy and live birth. WHAT IS KNOWN ALREADY: Despite its pivotal role in...

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PMID: 33575789
DOI: 10.1093/humrep/deab011

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