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Article

Repression of circRNA_000684 inhibits malignant phenotypes of pancreatic ductal adenocarcinoma cells via miR-145-mediated KLF5.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Mar 2021

Liu Xiumin, Zhong Lili, Jiang Weidong, Wen Dacheng

Abstract excerpt

BACKGROUND: Circular RNAs (circRNAs) are aberrantly expressed in pancreatic ductal adenocarcinoma (PDAC). In the current study, we investigated how circRNA_000684 affected the progression of PDAC, and how it regulated kruppel-like factor 5 (KLF5) and microRNA (miR)-145. METHODS: Differentially expressed circRNAs, miRs and genes related to PDAC as well as their targeting relationship were predicted using...

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Share to Carcinoma, Pancreatic Ductal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Kruppel-Like Transcription Factors

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Share to Neoplasms, Experimental

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Identifiers

PMID: 33563550
DOI: 10.1016/j.pan.2020.12.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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