Article
Proteo-Genomic Analysis of SARS-CoV-2: A Clinical Landscape of Single-Nucleotide Polymorphisms, COVID-19 Proteome, and Host Responses.
Journal of proteome research - 5 Mar 2021
Tushir Sheetal, Kamanna Sathisha, Nath Sujith S, Bhat Aishwarya, Rose Steffimol, Aithal Advait R, Tatu Utpal
Abstract excerpt
A novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19) and continues to be a global health challenge. To understand viral disease biology, we have carried out proteo-genomic analysis using next-generation sequencing (NGS) and mass spectrometry on nasopharyngeal swabs of COVID-19 patients to examine the clinical genome and proteome. Our...
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