Revisiting preeclampsia: a metabolic disorder of the placenta

Abstract excerpt

Preeclampsia (PE) is a leading cause of maternal and neonatal mortality and morbidity worldwide, impacting the long-term health of both mother and offspring. PE has long been characterized by deficient trophoblast invasion into the uterus and consequent placental hypoperfusion, yet the upstream causative factors and effective interventional targets for PE remain unknown. Alterations in the metabolism of...

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• Birth, Development, and Health
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• Pregnancy and preeclampsia studies