Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Osteoarthritic Subchondral Bone Release Exosomes That Promote Cartilage Degeneration.

Cells - 28 Jan 2021

Wu Xiaoxin, Crawford Ross, Xiao Yin, Mao Xinzhan, Prasadam Indira

Abstract excerpt

Altered subchondral bone and articular cartilage interactions have been implicated in the pathogenesis of osteoarthritis (OA); however, the mechanisms remain unknown. Exosomes are membrane-derived vesicles that have recently been recognized as important mediators of intercellular communication. Herein, we investigated if OA subchondral bone derived exosomes alter transcriptional and bioenergetic signatures of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aerobiosis
Share to Cartilage, Articular
Share to Cell Respiration

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chondrocytes

Share to Exosomes

Share to Hypertrophy

Share to Osteoarthritis

Share to Osteoblasts

Source

Open in PubMed Open full text

Identifiers

PMID: 33525381
DOI: 10.3390/cells10020251
PMCID: PMC7911822

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Osteoarthritic Subchondral Bone Release Exosomes That Promote Cartilage Degeneration.PMID 33525381Read ↗

Extracecellulr vesicles (EVs) microRNAs (miRNAs) derived from mesenchymal stem cells (MSCs) in osteoarthritis (OA); detailed role in pathogenesis and possible therapeuticsSemantic proximity Read ↗

Regulation of ferroptosis in osteoarthritis and osteoarthritic chondrocytes by typical MicroRNAs in chondrocytesSemantic proximity Read ↗

Exosomes and Bone DiseaseSemantic proximity Read ↗

The Application of Extracellular Vesicles Mediated miRNAs in Osteoarthritis: Current Knowledge and PerspectiveSemantic proximity Read ↗

The Research Progress of Exosomes in Osteoarthritis, With Particular Emphasis on the Mediating Roles of miRNAs and lncRNAsSemantic proximity Read ↗

Mechanism of osteoarthritis treatment by exosomesSemantic proximity Read ↗

Bone marrow mesenchymal stem cell-derived exosomes prevent osteoarthritis by regulating synovial macrophage polarization.Semantic proximity Read ↗

Exosomes Extracted from Human Umbilical Cord MSCs Contribute to Osteoarthritic Cartilage and Chondrocytes Repair Through Enhancing Autophagy While Suppressing the Wnt/β-Catenin PathwaySemantic proximity Read ↗

Role of MicroRNA, LncRNA, and Exosomes in the Progression of Osteoarthritis: A Review of Recent LiteratureSemantic proximity Read ↗

The Role of Exosomes in Bone Remodeling: Implications for Bone Physiology and DiseaseSemantic proximity Read ↗

MicroRNAs play a role in chondrogenesis and osteoarthritis (Review)Semantic proximity Read ↗

Exosomes derived from primary cartilage stem/progenitor cells promote the repair of osteoarthritic chondrocytes by modulating immune responsesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.