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Role of long non‑coding RNAs and related epigenetic mechanisms in liver fibrosis (Review)

18 Jan 2021

Abstract excerpt

Liver fibrosis is one of the major liver pathologies affecting patients worldwide. It results from an improper tissue repair process following liver injury or inflammation. If left untreated, it ultimately leads to liver cirrhosis and liver failure. Long non‑coding RNAs (lncRNAs) have been implicated in a wide variety of diseases. They can regulate gene expression and modulate signaling. Some of the lncRNAs...

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PMID: 33495817
DOI: 10.3892/ijmm.2021.4856

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