Article
Selective decrease in complement C2 hemolytic activity is a sensitive marker for cryoglobulinemia and active disease in hepatitis C patients.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Jul 2021
de Faria Atila Granados Afonso, Chaves Fernanda Correa, Ferraz Maria Lucia Gomes, Andrade Luis Eduardo Coelho
Abstract excerpt
BACKGROUND: Some HCV patients present low/non-detected C2 hemolytic activity (C2h) without apparent consumption of other Complement components (selective low/non-detected C2h). AIM: Characterization of the immunologic/clinical basis of this phenomenon. METHODS: C2h, HCV-viral load, cryoglobulinemia and Complement components were determined in 726 HCV patients, with sequential C2h determination in 189 patients....
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