Article
Genomic epidemiology of SARS-CoV-2 reveals multiple lineages and early spread of SARS-CoV-2 infections in Lombardy, Italy.
Nature communications - 19 Jan 2021
Alteri Claudia, Cento Valeria, Piralla Antonio, Costabile Valentino, Tallarita Monica, Colagrossi Luna, Renica Silvia, Giardina Federica, Novazzi Federica, Gaiarsa Stefano, Matarazzo Elisa, Antonello Maria, Vismara Chiara, Fumagalli Roberto, Epis Oscar Massimiliano, Puoti Massimo, Perno Carlo Federico, Baldanti Fausto
Abstract excerpt
From February to April 2020, Lombardy (Italy) reported the highest numbers of SARS-CoV-2 cases worldwide. By analyzing 346 whole SARS-CoV-2 genomes, we demonstrate the presence of seven viral lineages in Lombardy, frequently sustained by local transmission chains and at least two likely to have originated in Italy. Six single nucleotide polymorphisms (five of them non-synonymous) characterized the SARS-CoV-2...
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