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Potential role of the skin and gut microbiota in premenarchal vulvar lichen sclerosus: A pilot case-control study

14 Jan 2021

Abstract excerpt

The etiology of vulvar lichen sclerosus (LS) remains unclear; however, alterations in cutaneous and gut microbiota may be contributing to the pathogenesis of this inflammatory condition. To explore this hypothesis, we conducted a pilot case-control study, obtaining dermal swab and stool samples from prepubertal girls with vulvar LS (n = 5), girls with nonspecific vulvovaginitis (n = 5), and healthy controls (n =...

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PMID: 33444404
DOI: 10.1371/journal.pone.0245243

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