Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Long term follow-up results of deep brain stimulation of the Globus pallidus interna in pediatric patients with DYT1-positive dystonia.

Clinical neurology and neurosurgery - 1 Feb 2021

Ramezani Ghamsari Mona, Ghourchian Shadi, Emamikhah Maziar, Safdarian Mahdi, Shahidi Gholamali, Parvaresh Mansour, Moghaddasi Mehdi, Habibi Seyed Amir Hassan, Munhoz Renato P, Rohani Mohammad

Abstract excerpt

OBJECTIVES: Primary generalized dystonia (PGD) due to heterozygous torsin 1A (TOR1A) gene mutation (DYT1) is a childhood onset dystonia with rapid deterioration of symptoms, leading to severe disability in adolescence. Globus pallidus interna deep brain stimulation (GPi-DBS) has been shown to provide significant improvement in these cases. METHODS: This was a retrospective study of TOR1A mutation positive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Deep Brain Stimulation
Share to Dystonia Musculorum Deformans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Follow-Up Studies

Share to Globus Pallidus

Share to Molecular Chaperones

Share to Treatment Outcome

Share to Young Adult

Source

Identifiers

PMID: 33395620
DOI: 10.1016/j.clineuro.2020.106449

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Long term follow-up results of deep brain stimulation of the Globus pallidus interna in pediatric patients with DYT1-positive dystonia.PMID 33395620Read ↗

Dystonia: an update on genetics and treatment.Semantic proximity Read ↗

Shorter disease duration correlates with improved long-term deep brain stimulation outcomes in young-onset DYT1 dystonia.Semantic proximity Read ↗

GNAO1 Mutation-Induced Pediatric Dystonic Storm Rescue With Pallidal Deep Brain Stimulation.Semantic proximity Read ↗

TPK1 mutation induced childhood onset idiopathic generalized dystonia: Report of a rare mutation and effect of deep brain stimulation.Semantic proximity Read ↗

Pallidal deep brain stimulation for DYT6 dystonia.Semantic proximity Read ↗

Atypical phenotypes of DYT1 dystonia in three children.Semantic proximity Read ↗

Deep brain stimulation for myoclonus-dystonia syndrome with double mutations in DYT1 and DYT11.Semantic proximity Read ↗

The Effect of Globus Pallidus Interna Deep Brain Stimulation on a Dystonia Patient with the GNAL Mutation Compared to Patients with DYT1 and DYT6Semantic proximity Read ↗

Early stimulation of DYT1 primary generalized dystonia prevents from its secondary irreversible complications.Semantic proximity Read ↗

Sustained quality-of-life improvements over 10 years after deep brain stimulation for dystonia.Semantic proximity Read ↗

Novel THAP1 missense variant with incomplete penetrance in a case of generalized young onset dystonia showing good response to deep brain stimulation.Semantic proximity Read ↗

Dystonia-deafness syndrome caused by a β-actin gene mutation and response to deep brain stimulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.