Article
Temporal lobe malformations, focal epilepsy, and FGFR3 mutations: a non-causal association?
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 May 2021
Bernardo Pia, Budetta Mauro, Aliberti Ferdinando, Carpentieri Maria Luisa, De Brasi Daniele, Sorrentino Livio, Russo Carmela, D'amico Alessandra, Cinalli Giuseppe, Santoro Claudia, Coppola Antonietta
Abstract excerpt
Temporal lobe abnormalities and focal epilepsy have been documented in FGFR3-related clinical condition, including hypochondroplasia and Muenke syndrome. FGFR3 is expressed in the brain during development and could play a role in nervous system development and hippocampal formation. These observations suggest a non-casual association between temporal malformation, epilepsy, and FGFR3 mutations. Herein, we report...
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