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Mesenchymal Stem Cells Early Response to Low-Dose Ionizing Radiation

14 Dec 2020

Abstract excerpt

Introduction Mesenchymal stem cells (MSCs) are applied as the therapeutic agents, e.g., in the tumor radiation therapy. Purpose of the Study To evaluate the human adipose MSC early response to low-dose ionizing radiation (LDIR). Materials and Methods We investigated different LDIR (3, 10, and 50 cGy) effects on reactive oxygen species production, DNA oxidation (marker 8-oxodG), and DNA breaks (marker ɣ H2AX) in...

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PMID: 33381502
DOI: 10.3389/fcell.2020.584497

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