Plasma miR ‐1247‐5p, miR ‐301b‐3p and miR ‐105‐5p as potential biomarkers for early diagnosis of non‐small cell lung cancer

Abstract excerpt

BACKGROUND: Accumulating evidence shows that microRNAs are aberrantly expressed and exert essential roles in the tumorigenesis and tumor progression of non-small cell lung cancer (NSCLC). METHODS: The plasma miRNAs from five healthy donors and four NSCLC patients were profiled by miRNA microarray. The differentially expressed miRNAs from 154 primary NSCLC patients and 146 healthy donors were subjected to RNA...

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