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Bioinformatics analysis identifies COL1A1, THBS2 and SPP1 as potential predictors of patient prognosis and immunotherapy response in gastric cancer

21 Dec 2020

Abstract excerpt

BACKGROUND: The present study aimed to use bioinformatics tools to explore pivotal genes associated with the occurrence of gastric cancer (GC) and assess their prognostic significance, and link with clinicopathological parameters. We also investigated the predictive role of COL1A1, THBS2, and SPP1 in immunotherapy. MATERIALS AND METHODS: We identified differential genes (DEGs) that were up- and down-regulated in...

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PMID: 33345281
DOI: 10.1042/bsr20202564

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