Article
Identification of the Roles of Chromobox Family Members in Gastric Cancer: A Study Based on Multiple Datasets.
BioMed research international - 1 Jan 2020
Chen Zhuo-Yuan, Sun Shang-Xing, Zhu Si-Xian, Bu Jie
Abstract excerpt
BACKGROUND: As the important components in polycomb repressive complexes 1 (PRC1) and heterochromatin protein 1 (HP1), Chromobox (CBX) family members are involved in epigenetic regulatory function, transcriptional repression, and other cellular metabolisms. Increasing studies have indicated significant associations between CBX and tumorigenesis, which is a progression in different types of cancers. However, the...
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