Article
Evolution of MicroRNA Biogenesis Genes in the Sterlet (Acipenser ruthenus) and Other Polyploid Vertebrates.
International journal of molecular sciences - 15 Dec 2020
Fofanov Mikhail V, Prokopov Dmitry Yu, Kuhl Heiner, Schartl Manfred, Trifonov Vladimir A
Abstract excerpt
MicroRNAs play a crucial role in eukaryotic gene regulation. For a long time, only little was known about microRNA-based gene regulatory mechanisms in polyploid animal genomes due to difficulties of polyploid genome assembly. However, in recent years, several polyploid genomes of fish, amphibian, and even invertebrate species have been sequenced and assembled. Here we investigated several key microRNA-associated...
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