Article
Two Novel Cases of Autosomal Translocations in the Horse: Warmblood Family Segregating t(4;30) and a Cloned Arabian with a de novo t(12;25).
Cytogenetic and genome research - 1 Jan 2020
Ghosh Sharmila, Carden Candice F, Juras Rytis, Mendoza Mayra N, Jevit Matthew J, Castaneda Caitlin, Phelps Olivia, Dube Jessie, Kelley Dale E, Varner Dickson D, Love Charley C, Raudsepp Terje
Abstract excerpt
We report 2 novel autosomal translocations in the horse. In Case 1, a breeding stallion with a balanced t(4p;30) had produced normal foals and those with congenital abnormalities. Of his 9 phenotypically normal offspring, 4 had normal karyotypes, 4 had balanced t(4p;30), and 1 carried an unbalanced translocation with tertiary trisomy of 4p. We argue that unbalanced forms of t(4p;30) are more tolerated and result...
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