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Cell-free DNA promotes malignant transformation in non-tumor cells

10 Dec 2020

Abstract excerpt

Cell-free DNA is present in different biological fluids and when released by tumor cells may contribute to pro-tumor events such as malignant transformation of cells adjacent to the tumor and metastasis. Thus, this study analyzed the effect of tumor cell-free DNA, isolated from the blood of prostate cancer patients, on non-tumor prostate cell lines (RWPE-1 and PNT-2). To achieve this, we performed cell-free DNA...

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PMID: 33303880
DOI: 10.1038/s41598-020-78766-5

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