Article
Genomic analysis of group A rotavirus G12P[8] including a new Japanese strain revealed evidence for intergenotypic recombination in VP7 and VP4 genes.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jan 2021
Phan Tung, Ide Tomihiko, Komoto Satoshi, Khamrin Pattara, Pham Ngan Thi Kim, Okitsu Shoko, Taniguchi Koki, Nishimura Shuichi, Maneekarn Niwat, Hayakawa Satoshi, Ushijima Hiroshi
Abstract excerpt
Group A rotavirus is a leading cause of severe acute gastroenteritis worldwide. In this study, the first complete coding sequences of 11 RNA segments of human group A rotavirus G12P[8] in Japan were determined by an unbiased viral metagenomics. Its genomic constellation (VP7-VP4-VP6-VP1-VP2-VP3-NSP1-NSP2-NSP3-NSP4-NSP5 genes) was identified as G12-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1. When performing the genetic...
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