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Article

Liquid biopsy for BRAF mutations testing in non-small cell lung cancer: a retrospective study.

Journal of clinical pathology - 1 Jan 2022

Iaccarino Antonino, Pisapia Pasquale, Pepe Francesco, Sgariglia Roberta, Nacchio Mariantonia, Russo Gianluca, Gragnano Gianluca, De Luca Caterina, Troncone Giancarlo, Malapelle Umberto

Abstract excerpt

V-Raf murine sarcoma viral oncogene homolog B (BRAF) gene mutations have recently been approved to select advanced stages non-small cell lung cancer (NSCLC) patients for tyrosine kinase inhibitors treatments. In this setting, liquid biopsy may represent a valuable option for BRAF mutational testing in patients without tissue availability. Here, we reviewed 196 plasma based liquid biopsies analysed by an in-house...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33277344
DOI: 10.1136/jclinpath-2020-207107

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