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Origin, evolution and global spread of SARS-CoV-2

24 Nov 2020

Abstract excerpt

SARS-CoV-2 is the virus responsible for the global COVID19 pandemic. We review what is known about the origin of this virus, detected in China at the end of December 2019. The genome of this virus mainly evolves under the effect of point mutations. These are generally neutral and have no impact on virulence and severity, but some appear to influence infectivity, notably the D614G mutation of the Spike protein. To...

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PMID: 33274614
DOI: 10.5802/crbiol.29

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