Transition to secondary progression in relapsing-onset multiple sclerosis: Definitions and risk factors

Abstract excerpt

BACKGROUND: No uniform criteria for a sensitive identification of the transition from relapsing-remitting multiple sclerosis (MS) to secondary-progressive multiple sclerosis (SPMS) are available. OBJECTIVE: To compare risk factors of SPMS using two definitions: one based on the neurologist judgment (ND) and an objective data-driven algorithm (DDA). METHODS: = 19,318) were extracted from the Italian MS Registry....

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