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Article

Recombination and Positive Selection Differentially Shaped the Diversity of Betacoronavirus Subgenera.

Viruses - 16 Nov 2020

Forni Diego, Cagliani Rachele, Sironi Manuela

Abstract excerpt

The Betacoronavirus genus of mammal-infecting viruses includes three subgenera (Sarbecovirus, Embecovirus, and Merbecovirus), in which most known human coronaviruses, including SARS-CoV-2, cluster. Coronaviruses are prone to host shifts, with recombination and positive selection possibly contributing to their high zoonotic potential. We analyzed the role of these two forces in the evolution of viruses belonging...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33207802
DOI: 10.3390/v12111313
PMCID: PMC7698105

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