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Development and Verification of the Hypoxia-Related and Immune-Associated Prognosis Signature for Hepatocellular Carcinoma

1 Nov 2020

Abstract excerpt

BACKGROUND: It has been widely suggested that the association of hypoxia with the immune status within the microenvironment of hepatocellular carcinoma (HCC) is of great clinical significance. The present work was carried out aiming to establish the hypoxia-related and immune-associated gene signature to stratify the risks in HCC. PATIENTS AND METHODS: The ssGSEA and t-SNE algorithms were utilized to estimate the...

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PMID: 33204664
DOI: 10.2147/jhc.s272109

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