Article
Genomic Diversity and Evolution of Quasispecies in Newcastle Disease Virus Infections.
Viruses - 14 Nov 2020
Jadhav Archana, Zhao Lele, Liu Weiwei, Ding Chan, Nair Venugopal, Ramos-Onsins Sebastian E, Ferretti Luca
Abstract excerpt
Newcastle disease virus (NDV) infections are well known to harbour quasispecies, due to the error-prone nature of the RNA polymerase. Quasispecies variants in the fusion cleavage site of the virus are known to significantly change its virulence. However, little is known about the genomic patterns of diversity and selection in NDV viral swarms. We analyse deep sequencing data from in vitro and in vivo NDV...
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