Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SARS-CoV-2 Triggering Severe Acute Respiratory Distress Syndrome and Secondary Hemophagocytic Lymphohistiocytosis in a 3-Year-Old Child With Down Syndrome.

Journal of the Pediatric Infectious Diseases Society - 30 Apr 2021

Kim-Hellmuth Sarah, Hermann Matthias, Eilenberger Julia, Ley-Zaporozhan Julia, Fischer Marcus, Hauck Fabian, Klein Christoph, Haas Nikolaus, Kappler Matthias, Huebner Johannes, Jakob André, von Both Ulrich

Abstract excerpt

Down syndrome (DS) predisposes to severe immunologic reaction secondary to infectious triggers. Here, we report a pediatric DS patient with coronavirus disease 2019 (COVID-19) who developed a hyperinflammatory syndrome, severe acute respiratory distress syndrome, and secondary hemophagocytic lymphohistiocytosis requiring pediatric intensive care unit admission and treatment with steroids, intravenous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Monophosphate
Share to COVID-19 Drug Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to COVID-19 Testing

Share to Critical Care

Share to Immunoglobulins, Intravenous

Share to Lymphohistiocytosis, Hemophagocytic

Share to Prednisolone

Share to Systemic Inflammatory Response Syndrome

Source

Open in PubMed Open full text

Identifiers

PMID: 33188394
DOI: 10.1093/jpids/piaa148
PMCID: PMC7717321

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2 Triggering Severe Acute Respiratory Distress Syndrome and Secondary Hemophagocytic Lymphohistiocytosis in a 3-Year-Old Child With Down Syndrome.PMID 33188394Read ↗

COVID-19 in Children with Down Syndrome: Data from the Trisomy 21 Research Society SurveySemantic proximity Read ↗

COVID-19 in Children with Down Syndrome: Data from the Trisomy 21 Research Society SurveySemantic proximity Read ↗

COVID-19 Hospitalization is More Frequent and Severe in Down Syndrome and Affects Patients a Decade Younger.Semantic proximity Read ↗

Network analysis of Down syndrome and SARS-CoV-2 identifies risk and protective factors for COVID-19Semantic proximity Read ↗

Network analysis of Down syndrome and SARS-CoV-2 identifies risk and protective factors for COVID-19Semantic proximity Read ↗

Causes of Hospitalization in Children with Down SyndromeSemantic proximity Read ↗

An international survey on the impact of COVID-19 in individuals with Down syndromeSemantic proximity Read ↗

Clinical characteristics and comorbidities of COVID-19 in unvaccinated patients with Down syndrome: first year report in BrazilSemantic proximity Read ↗

Is any point to be skeptical regarding individuals with Down syndrome who are admitted with COVID-19?Semantic proximity Read ↗

Differences in Clinical Presentation, Severity, and Treatment of COVID-19 Among Individuals with Down Syndrome from India and High-Income Countries: Data from the Trisomy 21 Research Society SurveySemantic proximity Read ↗

Development of an effective immune response in adults with Down Syndrome after SARS-CoV-2 vaccinationSemantic proximity Read ↗

De novo variants in immune regulatory genes in Down syndrome regression disorderSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.