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Article

Molecular evidence of hybridization between pig and human Ascaris indicates an interbred species complex infecting humans.

eLife - 6 Nov 2020

Easton Alice, Gao Shenghan, Lawton Scott P, Bennuru Sasisekhar, Khan Asis, Dahlstrom Eric, Oliveira Rita G, Kepha Stella, Porcella Stephen F, Webster Joanne, Anderson Roy, Grigg Michael E, Davis Richard E, Wang Jianbin, Nutman Thomas B

Abstract excerpt

Human ascariasis is a major neglected tropical disease caused by the nematode Ascaris lumbricoides. We report a 296 megabase (Mb) reference-quality genome comprised of 17,902 protein-coding genes derived from a single, representative Ascaris worm. An additional 68 worms were collected from 60 human hosts in Kenyan villages where pig husbandry is rare. Notably, the majority of these worms (63/68) possessed...

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Identifiers

PMID: 33155980
DOI: 10.7554/eLife.61562
PMCID: PMC7647404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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