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Article

Overexpression of the ribosomal S30 subunit leads to indole-3-carbinol tolerance in Arabidopsis thaliana.

The Plant journal : for cell and molecular biology - 1 Feb 2021

Finkelshtein Alin, Khamesa Hala, Tuan Luu Anh, Rabanim Manely, Chamovitz Daniel A

Abstract excerpt

Indole-3-carbinol (I3C), a hydrolysis product of indole-3-methylglucosinolate, is toxic to herbivorous insects and pathogens. In mammals, I3C is extensively studied for its properties in cancer prevention and treatment. Produced in Brassicaceae, I3C reversibly inhibits root elongation in a concentration-dependent manner. This inhibition is partially explained by the antagonistic action of I3C on auxin signaling...

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PMID: 33128319
DOI: 10.1111/tpj.15062

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